White Paper

Bioburden: Addressing Microbial Contamination In Downstream Bioprocessing

Bioburden: Addressing Microbial Contamination In Downstream Bioprocessing

Bioburden control is an area of serious concern for both manufacturers of biologicals and suppliers to the industry. This white paper considers some of the risks related to downstream processing and presents recent developments by suppliers that help manufacturers mitigate these risks. Topics covered include improvements in raw material quality, equipment design, chromatography resin properties, and ways of working. Challenges specifically related to the sanitization of protein A chromatography resins are also discussed.

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