Bioprocess Intensification – Fast, Flexible And Efficient Solutions

Propelled by single-use systems (SUSs), biopharmaceutical companies are approaching the ideal of continuous bioprocessing. In addition to improving process integrity and decreasing production costs, SUSs have enabled exciting ways to configure, operate, and evaluate manufacturing steps. Sensitive process analytical technologies (PATs) and discriminating data analysis platforms are supplementing those developments, helping researchers to study and modify workflows in unprecedented ways. The goal now is to intensify: to apply increasingly nuanced process knowledge and growing technological capability in ways that simplify, condense, abbreviate, and  integrate distinct processes.

Intensification is easier said than done. And considering the industry’s ambiguous uses of the term, researchers need clear instruction about how to accomplish it. This compilation of articles details how Sartorius experts define process intensification and how end users can transition toward continuous processing.

November - December 2019 17(11-12)S BioProcess International