Newsletter | June 2, 2021

06.02.21 -- Boost Your CHO Cell Line -- Find The Best Media & Feed

 

CHO Cell Culture Media & Feeds: Selecting The Right Media

Matching media and feeds can be a strategy to increase output of your target molecule. Whether fed batch or perfusion, we make it easier for you to find the right media and feed for your specific need. Our chemically defined catalog media portfolio combines both Cellvento® and EX-CELL® Advanced cell culture media to offer a compatible and comprehensive range of off-the-shelf products to support all your Chinese Hamster Ovary (CHO) production processes.

Solutions For Cell Culture Media
4CHO Fed-batch Media And Feeds

EX-CELL® Advanced and Cellvento® 4CHO media support initial cell growth and production. The corresponding feeds replenish depleted nutrients required for cellular function and maintain and extend the production phase in fed-batch mode. High concentrated feed allows for a reduction of the added feed volume, increasing the volumetric productivity.

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Cellvento® 4CHO-X Expansion Medium

Cellvento® 4CHO-X Expansion Medium has been developed for seed train expansion and especially N-1 perfusion for CHO cell lines. It is formulated with a high nutrient concentration to achieve low cell specific perfusion rates (CSPRs) at high cell densities. Seed Train intensification requires a new type of medium that facilitates high cell densities and prepares the cells optimally for production.

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EX-CELL® Advanced HD Perfusion Media

EX-CELL® Advanced HD Perfusion Medium is a chemically defined cell culture medium designed specifically for intensified perfusion processes with CHO cells. This medium was developed to reach and maintain high cell densities at low cell specific perfusion rates (CSPR), while supporting high volumetric productivities of monoclonal antibodies and recombinant proteins in suspension culture. Next generation perfusion processes require a new type of medium to facilitate high productivity at low perfusion rates.

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