10.24.20 -- How Drug Development Benefits From End-To-End Thinking

Throughout a drug product development program, it is important to build robustness and flexibility into the manufacturing process. In this article, Dr. Kashif Ghaffar, process validation pharmacist, discusses what needs to be considered during product development in preparation for commercial manufacture.

Most oral solid formulations are designed to release the drug immediately after swallowing for rapid absorption into the bloodstream. However, some products have been developed to release the drug in a specific way following ingestion and provide a “controlled release” of the drug products. This article discusses some of the drug development technologies that provide a more specialized approach to oral dose delivery.

A pharmaceutical developer specializing in leveraging common compounds for new indications needed to transform a generic solid active pharmaceutical ingredient (API) into a commercial sterile injectable approved by regulators. Read how collaboration and the drive to find a workable solution led to a successful drug development program.