Newsletter | May 21, 2021

05.21.21 -- Powering Possibilities For The Future Of Combination Products

How Shorter Needles With Thinner Walls Are Set To Improve The Injection Experience In Chronic Care

This series of frequently asked questions covers the research and design mindset applied to the development of the BD Neopak™ XtraFlow™ solution and how the anticipated clinical benefits of 8 mm needles will support their broad adoption over time for subcutaneous drug delivery, particularly for use in chronic care settings.

Identifying Enhanced Needle Solutions And Integrated System Solutions To Serve The Chronic Disease Market

Demand for self-injection devices is rising, fueled by the prevalence of chronic diseases, biologics as a dominant therapeutic modality, and the increased demand for home healthcare. Needle innovations, including shorter needles with ultra-thin wall technology for prefilled syringes, support the delivery of drugs with greater volumes and viscosities, enhancing end-user experience.

Innovating In The Viscosity Design Space For Handheld Combination Products: A New 2.25 mL Autoinjector Platform

Biologics are contributing to quality of life improvements for chronic disease sufferers. Simultaneously, innovations in the drug delivery device space are allowing for chronic disease sufferers to manage their drug therapies from home. Discover an autoinjector platform that reconciles the demands of biologics with safety, reliability, and ease of use during self-injection.

Quality-By-Design Approach To Enable High-Dose Drug Delivery With Autoinjectors

Designing self-injection systems to deliver biological drugs into the subcutaneous space has specific challenges relative to those required for the safe and efficacious delivery of traditional pharmaceuticals. A quality by design (QbD) approach can manage all the unavoidable competing requirements and balance performance, robustness, and usability.

Impact Of Prefilled Syringe (PFS) Needle Dimensions On High-Volume, High-Viscosity Fluid Delivery

High-volume parenteral delivery systems require consideration of both functional design and human factors to enable successful and consistent, reliable delivery to the target tissue. Examine the influence of needle inner diameter and length on delivery time across a range of fluid viscosities using a prototype auto-injector device.