Droplet Digital PCR For Host Residual DNA Quantification

Source: Bio-Rad Laboratories, Inc.

Speaker - Musaddeq Hussain, Ph.D., Principal Scientist, Merck Research Laboratories

Droplet Digital PCR (ddPCR) for Host Residual DNA Quantification Biologics manufacturers must demonstrate that the level of host residual DNA (hrDNA) in a purified drug is safe. Current methods for doing so require extracting DNA from biopharmaceuticals purified from bacteria or mammalian cells. In this presentation, Dr. Hussain discusses an extraction-free method in which samples are subjected to digital PCR. Learn more about Bio-Rad Droplet Digital PCR Systems at