Exploring Takeda's Template For Sustainable Steam Generation

Takeda designed a model for delivering steam at 11 bar and up to 184 degrees using natural refrigerant and waste heat at one of its largest production sites.

Transforming Computer System Validation In The Life Sciences Industry

Regulators acknowledge how traditional CSV methods fail to meet modern demands for speed and flexibility. The scene is changing in favor of smarter, leaner validation.

Analyzing And Managing CDMO Project Risks Using Causal Mechanism & Effect Analysis

Since every sponsor–CDMO relationship can have widely different scopes, requirements, and procedures, this article focuses on the basic principles for analyzing and managing the risks of not achieving the relationship’s objectives.

A Sterilizing-Grade Membrane For Efficient Filtration Of Biologics

Higher flow rates and a smaller process footprint can create meaningful gains across sterile filtration steps. Explore the performance data and where efficiency improvements may be possible.

An Open-Source Modeling Tool For Suspended Continuous Lyophilization

Building on a continuous suspended-vial lyophilization workflow, process developers can model critical variables before doing physical experiments.

A Scalable Analytical Method For Quality-Driven AAV Characterization

AEX-HPLC has emerged as a robust, GMP-compatible analytical method for accurately characterizing AAV capsid composition, enabling consistent assessment of empty, partial, and full capsids to support product quality, process development, and regulatory readiness.

Step Into The Future Of Chromatography Automation

As downstream processing grows more connected and complex, chromatography remains a key automation challenge. See how greater flexibility and stronger control are shaping more practical workflows.

Process Intensification Through Downstream Connectivity

See how downstream steps can be linked into a coordinated workflow, with practical insight into automation, equipment integration, and process control for building a more efficient strategy.

Solving Glycoengineering Challenges Could Begin At The Cell Line

Researchers produced a panel of platform cell lines illustrating how glycoform selection can be made experimentally visible earlier in biologics development.

What Biopharma Often Overlooks In A Scheduled Shutdown

Shutting down an operating biologics facility upsets systems often designed for continuous operation. One expert shares his tips for preventing unnecessary problems.

LNP-Mediated Cell Transfection In Bioreactors Across Workflows

Lipid nanoparticles are redefining immune cell engineering. Delve into new data that demonstrates the performance across multiple cell types and bioreactor systems, supporting their potential workflows.

Towards A Universal LNP Platform For Multiplex Engineering

Multiplex engineering of T cells for solid tumors requires precise delivery. Emerging LNP approaches enable co-delivery of RNA and DNA, offering a safer, more scalable path beyond viral vectors.

Extrahepatic Delivery Of mRNA-LNP To Spleen

In vivo CAR-T approaches aim to reprogram T cells directly in the body using targeted lipid nanoparticles. Improved delivery to immune organs highlights new potential for scalable cell therapies.

mRNA LNPs Drive Safe, Effective Repeat Dosing In Disease Models

Well-designed lipid nanoparticles enable safe, efficient delivery. OVA-based models show how formulation choices shape efficacy, safety, and anti-tumor outcomes in melanoma research.

Discover A System That Can Be Used With Various Cell Culture Media

Evolving CAR T cell therapies are raising the bar for manufacturing. Advances in cell expansion and the shift to serum-free media are redefining how scalable, future-ready processes are designed.