Enabling Biologic Drug Delivery Of Volumes Beyond 1 mL With Ergonomic Injection Solutions For Targeted User Populations

By Tzvetelina Chevolleau, Natacha Montemuino, Megan Lan

BD NeopakT 2.25 mL With BD UltraSafe PlusT Passive Needle Guard Before Activation & Once Activated Straight

As high dose biologic formulations push the limits of self-injection into 1-2 mL formats and beyond, delivery systems that are intuitive and easy to use, and targeted to specific user populations, are becoming increasingly necessary. While self-injection systems are sometimes provided in the form of autoinjectors, manual injections, when given in an appropriate delivery format, can feasibly deliver injections that push the boundaries of volume or viscosity.

Most biologic drugs that are self-injected into the subcutaneous space today are available with volumes of 1 mL or less. However, biologic drugs are increasingly developed in high dosage formats, yielding high or viscosities. This leads to increasing injection times and injection forces, which could create difficulties for self-injecting patients.

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