Modern Improvements To Classic Technologies: Innovating Electrophoresis And Chromatography Upstream Of Protein Characterization To Speed Up Research

By Gunjan Choudhary and Laura Moriarty

When testing new drug therapies, it is essential to know the identity of the protein being tested. Whether that protein is the drug itself or the target for the drug, researchers must be absolutely sure of its identity and purity. Though many methods are used in the process of obtaining pure proteins, chromatography is commonly used to separate complex biological mixtures and isolate proteins of interest prior to downstream characterization.