Brochure | January 27, 2026

Put Your Oligo Synthesis In Good Hands: Column Selection Guide For Oligo Synthesis

Source: Cytiva
Oligo Column

Selecting the right column is essential for achieving consistent, high‑yield oligonucleotide synthesis. Learn how thoughtful column design—optimized liquid distribution, minimized dead volume, and compatibility with harsh reagents—directly supports uniform coupling efficiency at every cycle. This brochure walks through options for development‑scale to industrial‑scale workflows, from flexible small‑diameter columns ideal for method optimization to robust process columns engineered for operator safety and efficient handling of large reagent volumes. Gain clarity on when to use different formats, how column features influence performance, and how to streamline pre‑ and post‑synthesis steps with integrated systems that reduce exposure and manual intervention.

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