Raman As A Quality Control Tool For Cell Culture Media Preparation

Media preparation is crucial for producing safe, high-quality biopharmaceuticals. However, the limited parameters typically monitored during this process, pH and osmolality, are insufficient to prevent batch-to-batch variability and its effect on the production process. While these parameters are important, advanced analytical techniques can offer a more comprehensive understanding of the quality of the medium, reducing the cost and impact of errors during media preparation.

This application note showcases the increased knowledge Raman spectroscopy brings to the media preparation step. Explore results demonstrating the ability of Raman technology to easily differentiate between media with similar compositions and detect potential preparation errors that conventional analysis methods might miss.