Benzonase® endonuclease—the smart solution for DNA removal in biopharmaceutical production has proven its value for over 30 years. We balance efficiency and regulatory compliance by delivering reliability and high-quality manufacturing under GMP (ICH Q7). All Benzonase® endonuclease products share the same amino acid sequence (proven by LC-MS/MS mass spectrometry), robustness and activity. Additionally, to the stringent quality control and extensive documentation packages coming with Benzonase® endonuclease Emprove® Expert, the all new Safety Plus product elevates the high-quality level even further. Adding most recent manufacturing and analytical technologies it delivers elevated risk mitigation.
This bulletin explains a thorough analysis by our technical and regulatory experts that allowed us to come to the conclusion that Benzonase® endonuclease Emprove® Expert and Benzonase® endonuclease Safety Plus Emprove® Expert can be considered equivalent.