Biosimilar Manufacturing solution center

  1. Facility Design — Balancing Stainless-Steel, Single-Use, And Continuous Approaches To Manufacturing

    Although change may be intimidating, disruptive innovation allows manufacturers to achieve increased efficiency and quality.  Several drivers affect how the appropriate facility design and unit operations for a process are selected, making it imperative to properly evaluate each option. 

  2. S.U.B. Enhancements For High-Density Perfusion Cultures

    This study presents how strategic enhancements to the sparge and agitation systems of Thermo Scientific™ HyPerforma™ S.U.B.s have revealed the potential for a three- to four-fold improvement in mixing and mass transfer performance compared to legacy S.U.B. designs.

  3. Mass Transfer Of Single-Use Fermenters To Stirred Glass Bioreactors

    The HyPerforma S.U.F. performs similarly to stainless steel SIP/CIP fermentors, making it the best option against other single-use reactors that fall below the mark.

  4. Scale-up And Tech Transfer From 100 L SIP/CIP Vessel To The 300 L S.U.F.

    A collaborative study with a new customer with the objective of taking an existing, smaller preclinical E. coli process previously performed in stainless steel vessels and scaling it up quickly using the Thermo Scientific™ HyPerforma™ 300 L Single-Use Fermentor (S.U.F.)

  5. How Can Your Biomanufacturing Facility Benefit From Process Automation?

    With today’s complex manufacturing systems and processes, can a manufacturer afford to not have a centralized automation platform?

  6. How A New Factory-In-A-Box Is Helping Scale Up Manufacturing Of Viral Vector Based Therapies To Reach More Patients

    Manufacturing viral vector-based therapies such as vaccines and gene and cell therapies is complex, but a new manufacturing solution helps solve those challenges.

  7. Fujifilm Diosynth Biotechnologies Drives Flexibility And Efficiency In Their Biomanufacturing Platform Using Integrated Automation

    Through a successful implementation, Fujifilm was able to not only recognize the benefits an integrated automation platform offers but also the importance of working with an experienced partner.

  8. Biosimilars: Regulatory Trends And Manufacturing Considerations

    Regulatory approval of a biosimilar requires comprehensive knowledge of both the process and the molecule while process development with the end goal in mind will help to achieve a robust manufacturing process.

  9. Can A Shared Biomanufacturing Facility Be The Answer To The Demand Forecasting Dilemma?

    Using a shared biomanufacturing facility, a biomanufacturer can minimize its investment while mitigating the risks of demand uncertainty and maximizing time to market.

  10. The Top Trends Influencing Automation In The Life Science Industry 2018

    Trevor Marshall of Zenith Technologies discusses the impact that multi-product manufacturing facilities, single-use technologies, continuous manufacturing and industry 4.0 will have on automation.