Biosimilar White Papers

1. Three Options To Viral Vector Manufacturing Capacity 9/1/2020

   A recent Virtual Think Tank focused on the challenges and trends influencing design considerations for viral vector manufacturing facilities, and how they can impact companies developing cell and gene therapies.

2. Business Continuity Program Helps Maintain Operations In The Face Of Crisis 5/5/2020

   Get insights into implementing a robust business continuity management program that can help secure supply, reduce risks, and maintain quality in manufacturing operations, through a crisis situation.

3. Critical Considerations About The Future Of Global Cell Culture Bioprocessing 4/2/2019

   In today’s changing industry, it is critical we consider several factors about cell culture bioprocessing and the impact they will have on the future of patient treatment.

4. Addressing New Chromatography Challenges With Fiber Absorbents 6/2/2019

   An absorbent material using a novel proprietary structure overcomes the diffusional and flow limitations of packed bed chromatography purification systems and aims to address the capacity issues.

5. Strategies To Address The Viral Vector Manufacturing Shortage 3/5/2020

   Accelerating the production of your viral-vector based therapy requires understanding the strategies and cost-efficiencies available to address the viral vector manufacturing shortage.

6. How Buffer pH And NaCl Affect Size Exclusion Chromatography 4/22/2020

   Using a design of experiments approach, this study describes the effect of buffer pH and NaCl concentration on proteins purified by size exclusion chromatography.

7. Mechanistic Modeling Of Chromatography To Speed Up Process Development 3/2/2020

   Catch up on the current opportunities and challenges for using mechanistic modeling to simulate and predict chromatographic behavior and experiments in silico. 

8. Pairing Data Connectivity, Automation Ease Tech Transfer/Scale-Up 2/11/2020

   In biopharma, process data is used in many ways throughout process development and production phases. This article outlines how connectivity and comprehensive automation ease tech transfer and scale up.

9. Understanding And Controlling Raw Material Variation In Cell Culture Media 9/5/2019

   An organized effort across biopharma, including drug substance manufacturers and suppliers, is needed to address and meet the needs of industry regarding raw material quality and consistency.

10. Trends In Protein Separation And Analysis — The Advance Of Stain-Free Technology 4/7/2020

    Stain-free technology, a technology that existed in principle since early 2000 but was only commercialized in 2010 has changed the protein separation and analysis landscape in the past few years. This article focuses on how protein visualization is accomplished using stain-free technology, its advantages and concerns as well as how stain-free technology can change the way we carry out protein separation and analysis.