Biosimilar Insights
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A Scalable Single-Use Two-Step pDNA Purification Process
3/6/2024
Evaluate the performance of a single-use two-step plasmid purification process, and see how it compares to the existing three-step purification method.
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High-Titer rAAV Production In Bioreactors Using Producer Cell Lines
3/6/2024
Here, we detail the upstream process development and optimization for an AAV8-GFP proof-of-concept (PoC) producer single cell clone (SCC) in both batch and perfusion modes.
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Safer AAV Through Reduced Host-Cell DNA Encapsidation
3/6/2024
While most hcDNA molecules outside AAV particles can be eliminated during downstream processing, encapsidated hcDNA molecules remain largely undetectable. Learn how to overcome this critical issue.
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Producer Cell Line For Large-Scale Viral Vector Manufacturing
3/6/2024
Embrace the future of gene therapies and overcome challenges in large-scale viral vector manufacturing with a one-step process that ensures robustness and scalability.
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Cost Modeling Comparison Of Bioreactors To Produce Adherent Cell Products
3/6/2024
This study employs BioSolve software, a reference for cost analyses in the biopharmaceutical industry, to compare the upstream manufacturing costs between multitray stacks and the iCELLis™ bioreactor.
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Demand More From Your Oligo Synthesizer
3/4/2024
The market for oligonucleotide therapeutics is expanding, and the pipeline is diverse. Gain insight into how you can fast-track your molecule's development with verified synthesizers, columns, and scientific support and expertise.
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Imagine The Future: Enhanced Oligonucleotide Synthesis
3/4/2024
Learn about flexible control software that has revolutionized the way method creation, evaluation, and process optimizations for scale-up are completed.
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The Power Couple: CRISPR And Oligonucelotides
3/4/2024
Drug design using CRISPR depends on long guide RNA (gRNA) sequences. Find out how this love match between long oligos and CRISPR works.
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Five Essentials For Accurate Oligonucleotide Chemistry
3/4/2024
Explore five key areas in oligonucleotide chemistry where improvements will have a huge influence on your synthesis quality.
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The Innovator's Dilemma with Lumen Bioscience's Brian Finrow, J.D.
3/4/2024
In biotech, when "one of these things doesn't look like the other one," it can be a blessing or a curse. On one hand, scientific novelty is praised and rewarded. On the other, unfamiliarity breeds skepticism from the investment community. Brian Finrow, J.D. embraces that reality and the challenges that come with it.