Cytiva Cell datasheets catalogs app notes

1. Automated Cell Washing And Formulation In CAR T Cell Therapy Manufacturing 6/14/2024

   Explore data collected from a study utilizing healthy donors in a typical CAR T cell processing workflow without a transduction step from a cross-site validation study.

2. Review Of Applications And Processes In Fixed-Bed Bioreactors 5/6/2024

   Gain insights and guidelines for developing new processes in this review evaluating publications on the applications of single-use, scalable fixed-bed bioreactors for adherent cell culture processes.

3. Lentiviral Vector Production Using Single-Use Bioreactors 5/6/2024

   Here, we outline a scalable and robust upstream process developed for LVV production of HEK293T cells and demonstrate how to expand HEK293T suspension cells.

4. Comprehensive Solution For Autologous Cell Therapy Manufacturing 3/25/2024

   Explore detailed information regarding a comprehensive solution for cell therapy manufacturing that consists of two hardware components, specialized application software, and single-use kits.

5. Get Full Control Of Your T Cell Isolation 3/25/2024

   This study demonstrates the automated magnetic isolation of CD4/CD8+ cells from fresh or frozen leukapheresis using a functionally closed cell processing system paired with a modular application.

6. Exosome Isolation By TFF And Size Exclusion Chromatography 3/6/2024

   Here, we demonstrate a scalable workflow for the isolation of exosomes that combines tangential flow filtration for the concentration of exosomes followed by gentle size exclusion chromatography.

7. A Stable Cell Line For Inducible AAV Production 3/6/2024

   Delivering on the promise of AAV-based gene therapies beyond rare diseases will require large quantities of high-quality AAV, produced in a robust manner.

8. Using Automated Spinoculation For CAR T Cell Lentiviral Transduction 2/26/2024

   There is a growing demand for closed and automated lentiviral transduction steps in CAR T cell therapy workflows. Learn about a potential solution to address this unmet need.

9. Biacore™ SPR Systems For Titer Analysis Of Adeno-Associated Virus 10/13/2022

   We describe the performance of two assays for titer analysis of adeno-associated virus (AAV), serotype 2 and serotype 5, based on surface plasmon resonance (SPR).

10. AAV Production In Suspension HEK293 Cells With Single-Use Bioreactors 10/13/2022

    Explore how we expanded HEK293/HEK293T suspension cells from small cell culture (20 mL) in shake flasks up to a 10 L culture in a benchtop Xcellerex™ XDR-10 single-use bioreactor system.