Featured Articles

  1. mRNA Product Purification Process Strategies 2/15/2023

    Impurities from IVT can induce undesired immune responses and negatively impact translation efficiency. Explore the pros and cons of each option for mRNA purification.

  2. mRNA Product IVT Process Insights 2/15/2023

    In vitro transcription (IVT) allows a researcher to tailor synthesis and introduce modifications to produce a transcript. Learn about IVT along with process challenges and strategies.

  3. mRNA: Challenges And Strategies Related To The DNA Template Process 2/15/2023

    Encapsulated mRNA–LNP creation begins with synthesizing the DNA template. Explore insights on DNA template synthesis, the challenges and strategies of generating a DNA template using PCR, and more.

  4. Introduction To mRNA Manufacturing 2/15/2023

    The SARS-CoV-2 virus has changed the course of scientific research around mRNA. Learn about mRNA manufacturing, the structure of a mRNA molecule, RNase-free considerations, and more.

  5. A Guide To Polishing Chromatography In Process Development 2/6/2023

    Polishing chromatography describes the removal of minute amounts of impurities in the final phase of biopharmaceutical manufacturing. Explore considerations in developing your polishing steps.

  6. Using Mathematical Models To Improve Process Development 2/3/2023

    Explore the differences between statistical and mechanistic models along with their use in improving process development.

  7. How Distributed Automation And DPM Support Resilient Biomanufacturing 1/23/2023

    Learn how embracing digital transformation through the use of distributed automation and digital plant maturity can support productivity, efficiency, and resilience in biomanufacturing.

  8. Pursuing A “Biologic Revolution” With Vaxxinity's Mei Mei Hu 12/9/2022

    In a recent episode of The Business of Biotech, Vaxxinity's Mei Mei Hu explored how traditional vaccines and biologic therapies are converging to improve access to treatment on a global scale.

  9. Longhorn's Path To A Universal Influenza Vaccine 12/2/2022

    Thanks to the long-term planning of one biopharma family and some help from the U.S. Army, a universal influenza vaccine is coming soon to a clinical trial near you.

  10. Epigenomic Programming With Omega Therapeutics' Mahesh Karande 11/28/2022

    Designed at the intersection of engineering and biology, an exciting new drug mechanism aims to target and resolve a wide range of diseases at the pre-transcription level.