Featured Articles

81. Cell Therapy Scale-Up Strategies For Commercial Success 9/30/2020

    This article discusses options for cell therapy process development and validation that minimize risks through quality control (QC), optimization, scaling, closing, automation, and assay development.

82. Robust Process Development For cGMP Manufacturing Of Cell Therapies 9/24/2020

    By leveraging early decisions around process development, quality assurance, and quality control strategies, you can set yourself up for a successful cGMP manufacturing workflow. 

83. Platform Cell And Gene Therapy Media Development 9/9/2020

    This article highlights a case study on the removal of serum from the expansion step of an autologous cell therapy in a cost-effective manner without affecting cell performance.

84. Practical Tips To Develop A Lentivirus Packaging Cell Line 9/9/2020

    CAR T therapies are expensive, and lentiviral vectors production represents a large portion of these costs. These practical tips guide efficient development of a lentivirus packaging cell line.

85. 4 Critical Processes Impacting Cost Of Goods For Gene Therapy 8/11/2020

    There is an urgent need to drive down the costs of plasmids and viral vectors. Learn about the critical steps that impact cost and process innovations for viral vector manufacturing.

86. Key Considerations For Cryogenic Preservation And T Cell Viability 7/31/2020

    Illustrating how mammalian cells change when frozen, we offer cryopreservation strategies and identify temperatures at which it's safe to stop controlled cooling and transfer drug product to cryogenic storage.

87. Reducing Cost Of Goods For Gene Therapy 7/24/2020

    Frost & Sullivan's Virtual Think Tank brought together leading minds to discuss key challenges and other insights related to reducing the cost of goods (COGs) for gene therapy.

88. Regulatory Challenges For Viral Vectors For Cell And Gene Therapy 7/24/2020

    Frost & Sullivan's Virtual Think Tank series brought together leading minds in the cell & gene space to discuss current regulatory issues and key challenges in viral vector manufacturing.

89. Developing TIL Therapies: Sample Collection And Processing 7/16/2020

    While it has been advanced over many years, the process of developing TIL therapies still suffers from certain challenges. This article attempts to lay bare some of these challenges and discuss how novel technological solutions can help overcome them.

90. Tumor-Infiltrating Lymphocytes: What, Why, And How 7/1/2020

    As we explore immune mechanisms using technology, we find better ways to fight disease. Here, we focus on targeted, highly personalized cancer therapies called tumor-infiltrating lymphocytes.