Featured Articles
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Cell Therapy Manufacturing: The Supply Chain Challenge
4/1/2019
Overcoming the challenges of manufacturing and administering a complex product to any patient is critical for delivering cell therapies. Two industry experts detail strategies to meet supply chain challenges.
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Is A Rapid Cooling Step Needed When Freezing Cells For Cryopreservation?
3/6/2019
A “rapid-cooling nucleation step” is hypothesized to improve ice nucleation – an important event for good post-thaw outcomes. Explore how a rapid-cooling nucleation step affects viable cell count and activity of four cell lines.
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De-Mystifying, De-Risking Process Development With A CDMO
11/27/2018
An overview of how CDMOs can help companies get started in the world of CGT manufacturing, with considerations around timing of engagement to maximize commercial and clinical success.
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Factory-In-A-Box Scales Up Manufacturing Of Viral Vector Based Therapies
8/31/2018
Manufacturing viral vector-based therapies such as vaccines and gene and cell therapies is complex, but a new manufacturing solution helps solve those challenges.
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Effective Separation Of Full And Empty AAV Capsids By Anion Exchange
We show how Capto Q resin with dextran surface extenders, magnesium chloride (MgCl2), and the elution salt type (especially for rAAV9) significantly enhance separation.
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The Future Of Precision Medicine In China
China is quickly becoming a world leader in biopharma, with rapid build-out of gene and cell therapy production capacity and a robust pipeline of drugs in development.