product datasheets, catalogs, app notes

  1. Real-Time And In-Line Raman Spectroscopy For Glycan Quality Analysis 6/14/2024

    This study details the use of in-line Raman spectroscopy to monitor mAb glycan profiles within a production bioreactor, highlighting its potential for automation and customization.

  2. Enabling Accelerated Raman Model Calibration For Real-Time Monitoring 6/14/2024

    Raman spectroscopy is a key component of a PAT strategy. Evaluate an innovative workflow designed to streamline the integration of an in-line Raman analyzer for bioreactor applications.

  3. An Innovative Approach To Streamline Raman Implementation 6/14/2024

    Standard methods for building Raman spectroscopy models are often time-consuming and resource-intensive. Explore one-batch calibration and how its performance compares to other modeling techniques.

  4. Overcoming The Solubility Challenges Of Antibody-Drug Conjugates 6/3/2024

    Discover a chito-oligosaccharide that significantly improves the solubility of antibody-drug conjugates (ADCs) when included in the linker-payload construct.

  5. Simplifying CHO Cell Line Genetic Stability Testing 4/11/2024

    Here, we describe the use of whole genome sequencing to perform a comprehensive assessment of genetic stability in clonally derived CHO cell banks using the Aptegra™ CHO genetic stability assay.

  6. AAV Process Intensification Using High Salt Lysis And Salt Tolerant Endonuclease 3/25/2024

    In the production of adeno-associated virus (AAV) vectors, cell lysis involves challenges addressed through high salt concentrations and a salt-tolerant endonuclease, enhancing titer and infectivity.

  7. Novel Enzyme For Nucleic Acid Removal At High Salt Concentrations 3/25/2024

    Learn about a best-in-class solution designed for efficient nucleic acid removal at high salt concentrations.

  8. Characterization Of Host Cell Proteins By Liquid Chromatography - Mass Spectrometry 2/26/2024

    Explore an established liquid chromatography – tandem mass spectrometry (LC-MS/MS) method for characterization of residual HCPs in monoclonal antibody (mAb) products.

  9. A 2 mL Automated Perfusion Cell Culture Platform 12/5/2023

    The Mobius® Breez Microbioreactor is designed to support gentle, adaptable, and reproducible cell processes. Learn how it enables you to increase efficiency and reduce development timelines and costs.

  10. Accelerating Bulk Harvest Testing Using A CHO Animal Origin Free Virus Panel 10/19/2023

    Here, we describe the design and performance of a degenerate PCR-based approach to broad virus screening that can be used in testing bulk harvest material derived from CHO cells.