product datasheets, catalogs, app notes
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Quantitation Of Retrovirus-Like Particles (RVLPs) In CHO Derived Products
3/11/2022
Review key methods which are applied to ensure safety of such recombinant proteins, with a focus on alternate and superior methods to the standard transmission electron microscopy (TEM) method.
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Improve Fed-Batch Yields With EX-CELL® Advanced, Cellvento® Cell Culture Media Portfolios
2/15/2022
The biopharmaceutical industry is interested in developing high-titer fed-batch processes to meet increasing market demands and reduce manufacturing costs. This application note provides guidance and options for improving cell culture yield with off-the-shelf catalog products. Media combinations, dynamic fed-batch feeding options, and feed screening strategies suitable for diverse cell lines and manufacturing scenarios are presented.
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Multivariate Inter-Stage Batch Profile Monitoring And Future State Estimation For Efficient Manufacturing Operations
2/3/2022
How much quicker and easier would it be if we could know the process’s health by looking at a single metric rather than checking hundreds of parameters?
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Multi-Column Capture Chromatography
1/5/2022
Continuous capture chromatography allows for improved resin capacity, through continuous loading of multiple columns in series, reducing cost of goods.
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Mobius® FlexReady Solution With Smart Flexware® Assemblies For TFF
10/22/2021
The Mobius® FlexReady Solution with Smart Flexware® Assemblies is flexible, allowing you to have a single system for tangential flow filtration (TFF) at various scales.
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High Productivity CHO Cells: Optimizing A Perfused Seed Train
10/6/2021
This app note describes how N-1 perfusion using an expansion medium supports inoculation of a fed-batch, production bioreactor at a much higher cell density resulting in increased product titers.
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In-Line Real-Time Monitoring Of CHO Cell Culture Processes
9/16/2021
Demonstrating the Procellics™ Raman Analyzer with Bio4C® PAT Raman Software for in-line, real-time measurement of TCD, VCD and the concentration of glucose, lactate and ammonium.
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ProCellics Raman Analyzer With Bio4C PAT Raman Software
9/14/2021
Specifically designed for the bioprocessing industry, Procellics™ Raman Analyzer with Bio4C® PAT Raman Software enables you to perform in-line and real-time measurements of CPPs and CQAs, from process development to manufacturing.
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Glucose Control Using Raman Spectroscopy In CHO Cell Culture
9/2/2021
This application note describes the monitoring of glucose levels in a bioreactor and trigger automated addition of feed to maintain the desired concentration.
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Mobius® Power MIX Single-Use Mixing Systems
8/4/2021
The Mobius® Power MIX single-use mixing systems combine high performance mixing technology with design features that make them easy-to-use. The impeller design and motor are based on our magnetically coupled NovAseptic® mixing technology, a proven mixing technology in stainless steel tanks. These systems efficiently mix the most challenging buffers, media and biopharmaceutical ingredients.