product datasheets, catalogs, app notes

  1. Cogent® Lab Systems For TFF At Process Development Scale 3/23/2022

    One family of TFF systems with harmonized design and linear performance ensures successful and seamless scale-up or scale-down.

  2. The Evolution Of AI: Benefits To Biopharma 3/23/2022

    Considering the complexity of bioprocessing and the industry’s inherent “data siloes,” this paper focuses on how companies can use the power of smart data to leverage AI and drive additional insights.

  3. Chemically Defined Cloning Medium For Quality, Regulatory Risk Mitigation 3/18/2022

    We review the performance and stability of a novel, chemically defined cloning medium that accelerates clone isolation, reduces the risk of variability in protein quality, and reduces impurities.

  4. Quantitation Of Retrovirus-Like Particles (RVLPs) In CHO Derived Products 3/11/2022

    Review key methods which are applied to ensure safety of such recombinant proteins, with a focus on alternate and superior methods to the standard transmission electron microscopy (TEM) method.

  5. Improve Fed-Batch Yields With EX-CELL® Advanced, Cellvento® Cell Culture Media Portfolios 2/15/2022

    The biopharmaceutical industry is interested in developing high-titer fed-batch processes to meet increasing market demands and reduce manufacturing costs. This application note provides guidance and options for improving cell culture yield with off-the-shelf catalog products. Media combinations, dynamic fed-batch feeding options, and feed screening strategies suitable for diverse cell lines and manufacturing scenarios are presented.

  6. Multivariate Inter-Stage Batch Profile Monitoring And Future State Estimation 2/3/2022

    How much quicker and easier would it be if we could know the process’s health by looking at a single metric rather than checking hundreds of parameters?

  7. Multi-Column Capture Chromatography 1/5/2022

    Continuous capture chromatography allows for improved resin capacity, through continuous loading of multiple columns in series, reducing cost of goods.

  8. Mobius® FlexReady Solution With Smart Flexware® Assemblies For TFF 10/22/2021

    The Mobius® FlexReady Solution with Smart Flexware® Assemblies is flexible, allowing you to have a single system for tangential flow filtration (TFF) at various scales.

  9. High Productivity CHO Cells: Optimizing A Perfused Seed Train 10/6/2021

    This app note describes how N-1 perfusion using an expansion medium supports inoculation of a fed-batch, production bioreactor at a much higher cell density resulting in increased product titers.

  10. In-Line Real-Time Monitoring Of CHO Cell Culture Processes 9/16/2021

    Demonstrating the Procellics™ Raman Analyzer with Bio4C® PAT Raman Software for in-line, real-time measurement of TCD, VCD and the concentration of glucose, lactate and ammonium.