product datasheets, catalogs, app notes

81. High Productivity CHO Cells: Optimizing A Perfused Seed Train 10/6/2021

    This app note describes how N-1 perfusion using an expansion medium supports inoculation of a fed-batch, production bioreactor at a much higher cell density resulting in increased product titers.

82. In-Line Real-Time Monitoring Of CHO Cell Culture Processes 9/16/2021

    Demonstrating the Procellics™ Raman Analyzer with Bio4C® PAT Raman Software for in-line, real-time measurement of TCD, VCD and the concentration of glucose, lactate and ammonium.

83. Glucose Control Using Raman Spectroscopy In CHO Cell Culture 9/2/2021

    This application note describes the monitoring of glucose levels in a bioreactor and trigger automated addition of feed to maintain the desired concentration.

84. Mobius® Power MIX Single-Use Mixing Systems 8/4/2021

    The Mobius® Power MIX single-use mixing systems combine high performance mixing technology with design features that make them easy-to-use. The impeller design and motor are based on our magnetically coupled NovAseptic® mixing technology, a proven mixing technology in stainless steel tanks. These systems efficiently mix the most challenging buffers, media and biopharmaceutical ingredients.

85. Mobius® MIX Single-Use Mixing Solution 8/4/2021

    The Mobius® MIX single-use mixing solution delivers advanced technology for mixing pharmaceutical ingredients from intermediate to final drug products and for the preparation of process solutions, such as buffers and media. This single-use integrated mixing solution offers economic and operational efficiency, saving valuable processing and validation time.

86. How Millipak® Barrier And Millidisk® Barrier Filters Streamline Final Sterile Filtration 8/3/2021

    Millipak® Barrier and Millidisk®  Barrier filters contain hydrophilic and hydrophobic sterilizing-grade Durapore® 0.22 μm membrane. As they allow the passage of both liquid and air, they can be used to simplify wetting and drying during integrity testing of sterilizing filters. Learn more about the benefits of these filters and some guidance for implementation.

87. Single-Use Per Batch Biomolecule Purification Chromatography Membrane 7/20/2021

    Explore the performance of an advanced chromatography membrane when compared to currently available quaternary amine resins, membranes, and salt-tolerant primary amine membranes.

88. Pellicon 3 Cassettes Cleaning Methodology 7/13/2021

    This study demonstrates efficient cleaning strategies to enable multiple reuse of TFF cassettes for high concentration applications with SPTFF.

89. Comparison Between Experimental Data And Computational Fluid Dynamics In Mixing Applications 7/9/2021

    In biomanufacturing processes, mixing is ubiquitous and mixing trials are often necessary to assess if a technical solution is adapted for a given process step or to optimize process parameters. Discover how computational fluid dynamics can help in your mixing trials.

90. Cell Culture Media Mixing And Microfiltration: Reducing Risk With Single-use Technology 6/11/2021

    Cell culture media are complex mixtures of synthetic and biological components that provide the proper composition of nutrients for healthy cell propagation and high protein expression. Key concerns are to ensure product safety and purity. This paper presents our recommended methods for thoroughly mixing media, as well as reducing the risk of mycoplasma contamination.