Biosimilar App Notes & Case Studies
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Alkaline Stability Of Modern Protein A Chromatography Resins
7/12/2023
Explore results from a resin lifetime study with over 150 cycles, using clarified cell harvest in every cycle, which has been performed to evaluate the alkaline stability of three protein A resins.
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How To Protect A Modern Silicone Oil-Sensitive Biologic Drug For Self-Injection Of 2.25mL
4/25/2023
A customer experienced expensive project delays when they selected their “tried and tested” large volume, glass syringe system to package a drug to be used in an auto-injector for self-administration.
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Automated Bag Thawing System For CAR-T Cell Therapy Manufacturing
1/11/2022
The performance of the VIA Thaw CB1000 is compared to thawing in a water bath. The VIA Thaw™ dry thawing system shows comparable performance to a water bath with less handling.
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Higher Order Structure Of Proteins By Circular Dichroism Spectroscopy
9/30/2022
Learn more about the analytical development for mAbs and recombinant proteins
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AAV Production In Suspension HEK293 Cells With Single-Use Bioreactors
10/13/2022
Explore how we expanded HEK293/HEK293T suspension cells from small cell culture (20 mL) in shake flasks up to a 10 L culture in a benchtop Xcellerex™ XDR-10 single-use bioreactor system.
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Accelerating Bulk Harvest Testing Using A CHO Animal Origin Free Virus Panel
10/19/2023
Here, we describe the design and performance of a degenerate PCR-based approach to broad virus screening that can be used in testing bulk harvest material derived from CHO cells.
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Recombinant Protein Purification Optimization With HIC
5/1/2023
A step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
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Automating And Optimizing The Cell Harvesting Process
7/25/2022
Discover how we automate the process of optimizing cell harvesting and further minimize the potential for cell loss during wash steps.
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Protein L Affinity Resin Is Ready To Move To Manufacturing
7/12/2023
Discover a protein L affinity chromatography resin that is well suited for use in biomanufacturing and offers increased binding capacities compared to other resins.
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Reducing Lead Time & Optimizing Costs
8/2/2022
Explore how the use of this component platform produces significant savings, reduces elastomer SKU complexity, and increases speed to market.