Biosimilar App Notes & Case Studies
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Sterilizing Grade Filter Performance With Biologic Drugs
3/11/2024
Examine the throughput performance of sterilizing grade filters across moderate-to-high concentrations of mAbs and immunoglobulins as well as how filter selection can impact your process.
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Overcoming The Solubility Challenges Of Antibody-Drug Conjugates
6/3/2024
Discover a chito-oligosaccharide that significantly improves the solubility of antibody-drug conjugates (ADCs) when included in the linker-payload construct.
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Alkaline Stability Of Fc And VH3 Binding In Protein A Resins
5/1/2023
In this study, we looked at how different antibody binding sites of a protein A ligand are affected by cleaning in place (CIP).
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Alkaline Stability Of Modern Protein A Chromatography Resins
7/12/2023
Explore results from a resin lifetime study with over 150 cycles, using clarified cell harvest in every cycle, which has been performed to evaluate the alkaline stability of three protein A resins.
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Technology Transfer Considerations
6/13/2024
Speed and flexibility are crucial in the development of a new drug, from the laboratory to clinical trials and ultimately to the market. Explore considerations for a successful technology transfer.
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Bioreactor Scalability Supports Intensified Upstream Process Development
7/31/2023
In this study, key parameters for the Mobius® 3 L Single-Use Bioreactor and the 50-2000 L Mobius® iFlex Bioreactor impeller designs were characterized. Learn about bioreactor scalability for intensified processes.
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Optimizing Virus Bank Manufacturing
8/16/2024
Gain insight into two cases where clients were enabled to overcome obstacles during virus bank manufacturing.
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Accelerating Bulk Harvest Release Testing With A PCR-Based Solution
7/3/2024
Adventitious agent testing is frequently a bottleneck in downstream processing. Discover a PCR-based solution for manufacturing processes using CHO cells and animal origin-free components.
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Automation And Digital Solutions Can Help You Reach Your mRNA Manufacturing And Sustainability Goals
1/14/2025
Explore how digital solutions help streamline mRNA manufacturing by reducing costs, improving efficiency, and supporting sustainability by creating paperless processes for emerging therapeutics.
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Cell-Free Modeling Approach For Efficient Cell Culture Monitoring
6/14/2024
Learn about a novel cell-free modeling method for the efficient monitoring of cell cultures that has significant advantages over traditional approaches.