Biosimilar App Notes & Case Studies

  1. Demonstrated Strength And Durability Of Ultimus® Film 5/12/2023

    Here, we outline the development of Ultimus® film and summarize the strength and robustness tests conducted in accordance with the American Society for Testing and Materials (ASTM).

  2. Tangential Flow Filtration System Coupling To Enhance Solution Offerings 3/1/2023

    Discover a simple, easy, and versatile method for capsule and depth filtration of small volumes that moves research from cell harvest to purification as quickly and efficiently as possible.

  3. Developing A Large-Scale Tangential Flow Filtration Process 5/13/2024

    Discover a process that can be modified to fit your downstream process and serves as a complete solution for concentration and diafiltration.

  4. Maximize Product Recovery In Bulk Filtration And Filling Flow Paths 12/15/2022

    Explore a fill system designed to automate product draining and recovery within a batch to standardize processes and minimize non-recoverable hold-up within the filtration and distribution flow path sections.

  5. Generating A Robust Host Cell Line For A Cell Line Development Platform 11/14/2022

    Learn how cell performance within the context of the cell line development workflow was confirmed with the successful isolation of stable, high-producing clones from three model monoclonal antibodies.

  6. Lipid Nanoparticle Compositional Analysis By UHPLC-CAD 6/30/2023

    Explore results generated from an internal study using a proprietary mRNA-LNP formulation and UHPLC-CAD, a powerful technique for the analysis of compounds that do not contain chromophores.

  7. Implementation Of Raman Spectroscopy For In-Line Monitoring 11/3/2022

    Explore the development and implementation of Raman spectroscopy-based soft sensors for process monitoring of CPPs in bench scale, CHO cell, intensified seed trains (N-1).

  8. Process Control And Performance Of A Depth Filtration System 1/24/2023

    Explore a demonstration of strategic process control in terms of flow and pressure, by utilizing a depth filtration system, for effective depth filter processing and recovery of excess product.

  9. Protein L Affinity Resin Is Ready To Move To Manufacturing 7/12/2023

    Discover a protein L affinity chromatography resin that is well suited for use in biomanufacturing and offers increased binding capacities compared to other resins.

  10. Cell-Free Modeling Approach For Efficient Cell Culture Monitoring 6/14/2024

    Learn about a novel cell-free modeling method for the efficient monitoring of cell cultures that has significant advantages over traditional approaches.