Biosimilar App Notes & Case Studies
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Packing MabSelectâ„¢ And MabSelect SuReâ„¢ Resins Using Verified Methods
12/6/2024
Proper packing of MabSelect resins is crucial for efficient chromatography. Verified methods ensure stability, optimal flow, and reproducibility across scales using automated tools.
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Bioreactor Scalability Supports Intensified Upstream Process Development
7/31/2023
In this study, key parameters for the Mobius® 3 L Single-Use Bioreactor and the 50-2000 L Mobius® iFlex Bioreactor impeller designs were characterized. Learn about bioreactor scalability for intensified processes.
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Production Of A Highly Concentrated Monoclonal Antibody
10/4/2024
The production of a highly concentrated monoclonal antibody requires many process steps. Discover how to achieve a final mAb concentration above 200 g/L while maintaining critical quality attributes.
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Enabling Accelerated Raman Model Calibration For Real-Time Monitoring
6/14/2024
Raman spectroscopy is a key component of a PAT strategy. Evaluate an innovative workflow designed to streamline the integration of an in-line Raman analyzer for bioreactor applications.
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Integrated Services For Cell Line Preparation And Storage
10/8/2024
Explore a comprehensive suite of services for the manufacture, characterization, and storage of cell banks as well as the advantages of working with an experienced partner.
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Raman As A Quality Control Tool For Cell Culture Media Preparation
6/14/2024
Explore study results demonstrating how Raman technology easily differentiates between media with similar compositions and detects potential preparation errors that other analysis methods might miss.
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Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines
3/24/2025
Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.
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Standardize Scale-Up And Reduce Time To Market With Mixing Cartridges
7/21/2023
Despite the momentum of the RNA-LNP therapeutic market, significant manufacturing challenges remain. However, the right mixing could solve three of these key challenges regarding instrumentation.
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Getting CMC Right For Emerging Technologies
12/20/2023
Establishing a chemistry, manufacturing, and controls strategy that proves a clinical program is tightly controlled and can address risk is critical to avoiding the pitfalls that stall many promising therapeutics.
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Overcoming The Solubility Challenges Of Antibody-Drug Conjugates
6/3/2024
Discover a chito-oligosaccharide that significantly improves the solubility of antibody-drug conjugates (ADCs) when included in the linker-payload construct.