Biosimilar App Notes & Case Studies

  1. Best Practices For A Successful Bioprocess Technology Transfer
    9/10/2019

    A well-executed bioprocess technology transfer (tech transfer) is critical to ensure smooth knowledge transfer and optimal process reproducibility. If not executed properly, you risk reducing the quality and efficiency of your process. Waste time trouble shooting, and you may delay your time to market. In today’s global markets effective tech transfer is critical.

  2. Pulse Check: How To Assess Your In-House Biomanufacturing Capabilities
    6/18/2018

    By checking the pulse of your organization, you can identify gaps and develop a plan for how to address them, so you can make the right decisions at the right time.

  3. Don’t Let Insufficient Data Undermine Your CMO & CRO Selection Processes
    2/2/2018

    Selecting a partner is challenging, but with the right information you can simplify your efforts and increase your likelihood of making the best decision. 

  4. How Services Marketers Can Own Their Performance Measures
    1/29/2019

    Service marketers can take control of their marketing performance by implementing credible marketing effectiveness measures and creating their own narrative.

  5. Optimization Of Midstream Cell Lysis And Virus Filtration Steps In An Adenovirus Purification Process
    9/10/2018

    Here we describe screening of detergents for release of adenovirus from HEK293 host cells to replace the traditionally used detergent Triton™.

  6. Fujifilm Diosynth Biotechnologies Drives Flexibility And Efficiency In Their Biomanufacturing Platform Using Integrated Automation
    8/30/2018

    Through a successful implementation, Fujifilm was able to not only recognize the benefits an integrated automation platform offers but also the importance of working with an experienced partner.

  7. A Model System For Fast Screening Of Optimal Protein Purification Conditions
    6/3/2019

    This study in an overview of a model system for screening optimal protein purification conditions on a mixed-mode cation exchange resin using a statistical software–generated design of experiment (DOE) model with ChromLab Software’s Multivariable Scouting (MVS) function on the NGC Chromatography System.

  8. Process-Economy Simulation Of mAb Capture Step With Protein A Chromatography Resin
    10/10/2018

    Calculation examples that highlight scenarios where the enhanced capacity and alkaline‑stability of MabSelect PrismA can provide process economic benefits to large‑scale mAb processing.

  9. Improved Process Economics Of Humira Biosimilar Purification
    1/10/2019

    This application note proposes an alternate but equally effective approach to biosimilar purification, by substituting a less expensive ion exchange resin for the affinity capture step.

  10. Why Invest In Emerging Markets Now
    10/10/2018

    Unexplored and emerging markets are an attractive prospect for biopharma companies looking to expand. But when it comes to ensuring success, what’s the wisest way to invest?