Biosimilar App Notes & Case Studies
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Determining RNA Integrity And Purity By Capillary Gel Electrophoresis
6/30/2023
To ensure mRNA product quality, it's important to confirm the integrity of the RNA. Examine the results of a study challenging the performance of the CGE method in assessing mRNA integrity and purity.
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Determining The Power Numbers For A Single-Use Mixing System
6/19/2024
In designing a mixing process for scale-up, the power number is a critical parameter. Explore the determined power numbers for a single-use mixer at various mixing speeds and fill levels.
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Automation And Digital Solutions Can Help You Reach Your mRNA Manufacturing And Sustainability Goals
1/14/2025
Explore how digital solutions help streamline mRNA manufacturing by reducing costs, improving efficiency, and supporting sustainability by creating paperless processes for emerging therapeutics.
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Get Full Control Of Your T Cell Isolation
3/25/2024
This study demonstrates the automated magnetic isolation of CD4/CD8+ cells from fresh or frozen leukapheresis using a functionally closed cell processing system paired with a modular application.
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Using Automated Spinoculation For CAR T Cell Lentiviral Transduction
2/26/2024
There is a growing demand for closed and automated lentiviral transduction steps in CAR T cell therapy workflows. Learn about a potential solution to address this unmet need.
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Extractables In Single-Use Systems Used In ADC Manufacturing
9/23/2024
To address concerns about using organic solvents in the ADC process, extractables studies were conducted on a disposable chromatography column housing and two different disposable flow paths.
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Aseptic Filling Solution Enhances Sterility Assurance for Pharma Manufacturer
11/21/2024
Emergent BioSolutions upgraded its Winnipeg site with the Cytiva SA25 aseptic filling workcell to improve sterility assurance, product flexibility, and regulatory compliance for CGT manufacturing.
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Packing MabSelectâ„¢ And MabSelect SuReâ„¢ Resins Using Verified Methods
12/6/2024
Proper packing of MabSelect resins is crucial for efficient chromatography. Verified methods ensure stability, optimal flow, and reproducibility across scales using automated tools.
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Monitoring Bioprocesses In A Light Environment Using Raman Spectroscopy
6/14/2024
Discover an advanced solution to facilitate the implementation of Raman technology at both laboratory and manufacturing scales in a normal light environment.
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Fab Fragment Development And Manufacturing For Clinical Trials
6/12/2024
Explore the outcomes of implementing an accelerated approach to process development and manufacturing for a project that was crucial for the future of Acticor Biotech and its therapeutic candidate.