Biosimilar App Notes & Case Studies

1. Integrated Services For Cell Line Preparation And Storage 10/8/2024

   Explore a comprehensive suite of services for the manufacture, characterization, and storage of cell banks as well as the advantages of working with an experienced partner.

2. Enabling Accelerated Raman Model Calibration For Real-Time Monitoring 6/14/2024

   Raman spectroscopy is a key component of a PAT strategy. Evaluate an innovative workflow designed to streamline the integration of an in-line Raman analyzer for bioreactor applications.

3. Improving Bioprocess Monitoring And Control With Multivariate Data Analysis 12/9/2024

   Learn about multivariate data analysis (MVDA) techniques, like PCA and PLS, that enable near real-time monitoring, prediction, and optimization of biomanufacturing processes.

4. Review Of Applications And Processes In Fixed-Bed Bioreactors 5/6/2024

   Gain insights and guidelines for developing new processes in this review evaluating publications on the applications of single-use, scalable fixed-bed bioreactors for adherent cell culture processes.

5. Mobius® ADC Reactor Performance 10/22/2024

   Learn about a family of single-use ADC reactors that has been developed to offer a safer and more efficient ADC production method than traditional mixing systems and meet the industry's growing needs.

6. Real-Time And In-Line Raman Spectroscopy For Glycan Quality Analysis 6/14/2024

   This study details the use of in-line Raman spectroscopy to monitor mAb glycan profiles within a production bioreactor, highlighting its potential for automation and customization.

7. Automation And Digital Solutions Can Help You Reach Your mRNA Manufacturing And Sustainability Goals 1/14/2025

   Explore how digital solutions help streamline mRNA manufacturing by reducing costs, improving efficiency, and supporting sustainability by creating paperless processes for emerging therapeutics.

8. AAV Process Intensification Using High Salt Lysis And Salt Tolerant Endonuclease 3/25/2024

   In the production of adeno-associated virus (AAV) vectors, cell lysis involves challenges addressed through high salt concentrations and a salt-tolerant endonuclease, enhancing titer and infectivity.

9. Exosome Isolation By TFF And Size Exclusion Chromatography 3/6/2024

   Here, we demonstrate a scalable workflow for the isolation of exosomes that combines tangential flow filtration for the concentration of exosomes followed by gentle size exclusion chromatography.

10. Balancing Protein A Resin Cost, Performance, And Productivity 7/31/2025

    Optimizing input parameters like DBC, flow rate, and resin durability is key to boosting productivity in downstream bioprocessing. Discover how to tailor resin choices to meet your specific process requirements.