Biosimilar App Notes & Case Studies

  1. Modular Approaches For Diverse Molecules: Reinventing Smart Bioprocessing
    2/23/2018

    Smart bioprocessing uses bioinformatics, lab-scale processing, and analytics to create efficient and cost-effective production processes that can be verified at lab-scale before scale-up.

  2. Making The Business Case For Vaccine Manufacturing
    10/10/2018

    Vaccines are absolutely crucial for maintaining global health, but are a challenge to develop and manufacture. How can businesses ensure profitability while providing low prices for developing countries?

  3. Adenovirus Production In Single-Use Xcellerex™ XDR-10 Bioreactor System
    9/10/2018

    This application note describes the production of adenovirus in HEK293 cells cultured in HyClone™ CDM4HEK293 culture medium.

  4. Can A Shared Biomanufacturing Facility Be The Answer To The Demand Forecasting Dilemma?
    8/13/2018

    Using a shared biomanufacturing facility, a biomanufacturer can minimize its investment while mitigating the risks of demand uncertainty and maximizing time to market.

  5. Are You Ready For The Future of Biomanufacturing?
    1/19/2018

    As novel medicines become a larger part of the industry's portfolio, it is critical you secure a supply chain and manufacturing processes that produce drugs in a reliable, cost-effective way. 

  6. Amgen’s Digital Transformation: Link Suppliers' Raw Material Data To Patients
    10/19/2018

    Using its Supplier Relationship Excellence program, Amgen opened the lines of communication with suppliers and created a feedback loop where data can be shared to optimize operational performance. 

  7. Improved Process Economics Of Humira Biosimilar Purification
    1/10/2019

    This application note proposes an alternate but equally effective approach to biosimilar purification, by substituting a less expensive ion exchange resin for the affinity capture step.

  8. Quantitating Binding Similarities In IgG Fcγ Receptor Analysis
    5/23/2019

    Critical quality attributes (CQA) are fundamental to regulatory compliance and in drug development and manufacturing. Find out how surface plasmon resonance has been applied for protein characterization of antibody effector function.

  9. Adenovirus Production In Single-Use Bioreactor System
    3/8/2019

    Rocking bioreactor systems can shorten the seed train prior to inoculation and provide optimized growth conditions for sensitive cells. This study presents a robust production of adenovirus using such a system.

  10. What’s New in U.S. Biosimilar-Land?
    1/16/2018

    A lot has been promised with the introduction of biosimilars, but can they really deliver a viable alternative treatment to biologics at a substantial savings?