Biosimilar App Notes & Case Studies

1. Real-Time And In-Line Raman Spectroscopy For Glycan Quality Analysis 6/14/2024

   This study details the use of in-line Raman spectroscopy to monitor mAb glycan profiles within a production bioreactor, highlighting its potential for automation and customization.

2. Ultra-Low Cross-Linked Microgel Purification 2/24/2026

   ULC microgel purification is often slowed by linear polymer contamination and limitations of centrifugation. Explore how hollow fiber TFF improves filtration efficiency and supports scalable processing.

3. Can Your Biopharma Team Keep Unplanned Downtime At Bay? 3/10/2026

   Learn how teams reduce downtime, strengthen compliance, and respond quickly to equipment issues through proactive maintenance, smart spare parts planning, and digital troubleshooting tools.

4. TFF Cassettes With 100 kDa Membranes For RNA And LNP Applications 7/3/2024

   This study showcases the performance of regenerated cellulose flat sheet membranes with a 100 kDa molecular weight cutoff for UF/DF of RNA molecules by TFF.

5. Automated PUPSIT For Drug Product Applications 1/13/2026

   Automated filtration systems streamline PUPSIT, leak testing, and integrity checks to ensure sterile drug product processing. Learn how these methods improve contamination control and compliance.

6. Non Animal Origin Squalene For High-Risk Applications 7/21/2025

   Explore an ethical and sustainable alternative to shark-derived squalene that is backed by robust data to deliver identical performance in vaccine formulations without environmental compromise.

7. How To Successfully Isolate Your T Cells 10/7/2024

   Explore the results of a study focusing on the early stages of the CAR T cell workflow, specifically the initial washing of leukapheresis followed by the isolation of T cells.

8. Review Of Applications And Processes In Fixed-Bed Bioreactors 5/6/2024

   Gain insights and guidelines for developing new processes in this review evaluating publications on the applications of single-use, scalable fixed-bed bioreactors for adherent cell culture processes.

9. Performance Of Mobius® Bag Assemblies With Ultimus® Film In Truck Shipping Simulation Test 10/29/2024

   Explore findings from a study testing Mobius® single-use bags under rigorous shipping conditions, demonstrating the suitability for transporting various liquid volumes while preserving their integrity.

10. Selecting A Platform Filter For High Concentration mAbs 4/9/2025

    Read more about how Fujifilm Diosynth Biotechnologies evaluated a prime filter with challenging simulant solutions and how the experimental data confirmed superior performance, which demonstrated twice the throughput.